1st ultrasound 10/1: TWO beautiful heartbeats! Please select a reason for escalating this post to the WTE moderators: Connect with our community members by starting a discussion. Round Two Result 4/30: Harsh BFN But I believed we switched because of not getting eggs. 0000003164 00000 n The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. 11 retrieved, 10 matured and fertilized and 4 blasts and 1 normal. I'm 42 y/o and had my 2nd egg retrieval on 4/16. The example above shows 9 days of stimulation (FSH shots). What to Expect supports Group Black and its mission to increase greater diversity in media voices and media ownership. 2TFR'ed. I have no idea if that's true but it gave me hope and made me feel better. Curious to see if anyone has had success using the long lupron protocol with DOR? Stimmed for 12 days and had retrieval on day 14. Your stories have all made me feel better. Your post will be hidden and deleted by moderators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. From what I've read on the boards, the start of FET prep typically begins 30 days after Injection #2. Hi ladies just looking for any inspiring stories! Will I start to see the follicles and it's just too early?? Canceled due to ovulation through Lupron. MENTS I married at 39 and got pregnant naturally a year later, then miscarried. Thanks!! So for this 3rd FET my dr has added in estrogen injections. Hello! I dont want to keep trying protocols and not succeeding. Countless BFN(s) I also turned 39 this week so alsonfeeling dejected why I cant make normal embryos. Dr. C apologized for the fucking nightmare of a cancelled cycle, and implied that maybe the other doctor we were seeing in the practice should have put the breaks on way before day 10 because there was LITERALLY NO RESPONSE. thanks! I did 9 IVF attempts in 2 years - high stim, low stim, mid-stim, estrogen-priming. I did do both natural start and primed and my response was the same. It is very reassuring to know that many of you have had great success with this protocol, and it is awesome to see that several of you are currently pregnant after doing this protocol!! 14 and 13. And this time we are also going to do 225 follistim (x2/day) and 75 menupur (x2/day). At 39, you still have a good chance. Estrogen priming and the agonist-antagonist conversion protocol is at least as successful as the microdose flare protocol based on medical data. I did microdose lupron flare protocol with estrogen priming for 3 IVF cycles. As access age, Tarlatzis BC. The patient is given twice-weekly injections of estradiol valerate (Delestrogen) for a period of 8 days whereupon COS is initiated using a relatively high dosage FSH- (Follistim, Fostimon, Puregon or Gonal F), which is continued along with daily administration of GnRH antagonist until the "hCG "trigger." Reddit and its partners use cookies and similar technologies to provide you with a better experience. Initial was 12. However other had mature egg and we did Icsi by it didn't grow from there. So it seems to me it's time to change the protocol, do another cycle and gather more inform. We started our second cycle on Friday (7th). 0000003240 00000 n 0000001323 00000 n . Did you change protocol? Just curious-What was your medicine protocol. '13 Attempt at IVF #1 with Lurpon Flare- Canceled due to ovulation through Lupron.Sept. 1 10cell Grade 4, 1 8cell Grade 4. This seems really high to me. Any advice is welcome! Yay! And where there is variation? 2TFR'ed. I have no input on EPP but I am so excited you're starting up!!! 1Frostie. My new protocol is Estrogen Priming Antagonist. Guessing my trigger will be on 10/1. 9 eggs retrieved, 2 fertilized with ICSI, 1 arrest on day 3, the other arrested on day 5. Second retrieval was agonist with lupron, and we ended up with two decent quality embryos (3BB, 4BB), one of which became my newborn daughter, who I am currently breastfeeding. Press question mark to learn the rest of the keyboard shortcuts. I am 42 and after 1 failed IUI and 1 failed IVF, I am now starting my second round IVF with the lupron flare and ICSI. Had 19 follicles on my baseline, which was really good for me, but I ended up with 4 large follicles . They said my FSH and AMH levels were really good too so i just think i'm a poor responder to IVF in general! Er 6- jan 2021- GH and estrace priming for 4 days. It's not your first rodeo here." Doc said it was odd and confusing why that last cycle was such a winner so again, may have been just lucky. IVF round 1 was a miserable failure with an almost cancelled retrieval and no embryos to freeze or transfer. I do have DOR and Endo, Amh 0.69. afc and fish comparable to yours or slightly worse. Need advice. I am asking about supplements like CoQ10 and DHEA. Thanks. The major difference is that, by cutting the dose of Lupron down to one sixth of the routine dose, and by giving it twice daily, the Lupron actually turns the pituitary gland on rather than off, producing major release of FSH. IVF protocol. I badly want to be a mom. Er 3- 2019 - follistim 450 iu + menopur 150 iu , bcp priming - 6 mature eggs- 2 day 5 blasts but both abnormal. 2005-2023Everyday Health, Inc., a Ziff Davis company. Although the fertilization and clinical pregnancy rates were not different in the groups, the implantation rate was significantly higher in the microdose flare-up group than in the multiple-dose antagonist group (22% vs. 11%). We did EPP for this last IVF (#4) and it was our best cycle by far. So, yes, you can have better results the second time around and I really hope thats true for you! Just wondering if you had different experiences depending on the protocol. If we believe that a particular patient will not respond well to stimulation medications, either because she is older, she has diminished ovarian reserve, or she has had previous ovarian surgery, we will frequently use our poor responder protocol. :), I'm confused by all the information out there for women over 40. Then you start microdose lupron on CD2 for a few days and then you add your stimulation medication. Has anyone used this protocol and had any success? You can read up on estrogen priming (also . I feel like it's always better to go slow & steady. 0000006212 00000 n What my clinic is proposing, however, is starting. After the 6th negative pregnancy test, they did a "pregnancy loss" bloodwork panel. I hope this helps,I conceived my son naturally on 50 mg clomid at 39. Four mature eggs were retrieved. A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. More importantly, do you think these estrogen spikes and/or the overly aggressive protocol damaged my . with this protocol, and a general timeline for when things happen when you don't do BCP suppression beforehand New comments cannot be posted and votes cannot be cast. Previous studies comparing E2 priming and leuprolide flare IVF protocols report that E2 priming protocols result in longer cycles and higher total gonadotropin dose with similar oocyte yield, fertilization, and pregnancy rates; though, one report suggests a trend toward higher quality embryos in E2 priming cycles. I am hoping and praying that all 4 make it to day 5 for. 1. Ipersonally didnt want to put my body thru all those meds again so we just adopted 3 young healthyembryos from a family similar to ours and we are so excited our son will end up with a sibling or maybe two! My E2 never soared like some women'son the day of my trigger my E2 was only 1563, but I still got 16 eggs. Stimulation Day 4 Come in for an E2 and LH blood test. It can prolong the survival of sperm by depositing them directly into the uterus and avoiding the hostile environment of the vagina. I am not familiar with it, but I will definitely some research. Beta3 9/14: 1224! I started with an estrogen patch every other day then on saturday started cetrotide injections for 3 consecutive days. Dr. C will now be our doctor point of contact! My FSH is 12. I would like to know if any has been on the EPP/ MDL protocol ? Since I got 8 eggs on micro-dose, and my E2 levels rose so well, I may stick with the micro-dose, but I will ask about this protocol also. Now is the perfect time to start your Baby Registry! Estrogen primed microdose lupron flare protocol karela After 5-6 days of stimulation an antagonist is added to prevent ovulation until the day of. Create an account to follow your favorite communities and start taking part in conversations. and also why some of us seem to have Pills that are not really needed. Best of luck to ya and I hope your next cycle proves 'the one'!!! We had 3 failed IUIs- great response, great sperm count, great progesterone, then negative. We respect everyones right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expects Terms of Use. Beta 1/22: 14 Beta 1/24: 24 Beta 1/26: 28 It's so hard to imagine that something might work when everything else hasn't. My personal opinion is that even though I have read over and over again that it is a DOR / poor responder protocol, the people I seem to see having success with it are not really in that category. i will try to check back.. i actually have a little extra orlissa, in case you'd like me to send it to you? skin rash, hives, or itching. xref 1Frostie. My AFC was 7 on day 3. Lower doses like 300 iu follistim didn't work for me. Did they give you a plan for your cycle yet? They are concerned about egg quality. My husband doesn't even want donor eggs, so.donor eggs.might.not be an option for now. I'm reading so much about low stim for DOR and over 40 works better that make me very nerveous about trying high doses. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. Estrogen Primed Antagonist Protocol. Changing IVF protocols - any success or thoughts? Has anybody here had an experience with this protocol and was it successful? Wegot completely different results at 43 I got 6 eggs mature eggs & 3 embryos. Intrauterine Insemination (IUI) improves the processes involved in natural sexual intercourse to help you conceive without undertaking IVF. I have an IVF consult in two weeks and although I've got my questions (mostly from the wise women on this board) I'm trying to get more information on 'protocols'. My little one is a success story from MDL! In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. Our beautiful little girl arrived January 2015! Your nurse will phone you with instructions by 5:00PM this day. (Not so) Short summary - DH and I have been ttc since May 2015, two early m/c. Success with Long Lupron Protocol for DOR ? Advanced Fertility Care Injection Teaching Videos. I did lupron stop protocol for IVF#1, but I was still oversuppressed. :) But after my horrible #2 cycle, knowing I really would probably only do one more I gave it all I had for three-four months. sudden, severe decrease in blood pressure and collapse. Not attempted transferring anything yet. Hope it makes the difference for you! I am 42. Canceled due to ovulation through Lupron. Been feeling lonely lately as friends and family are getting pregnant around me (even friends who also struggled with fertility issues), so looking for somewhere else to hopefully find people to connect with. The LDL protocol was initiated with late luteal lupron (0.25 mg daily). I tried an antagonist with no down regulation and of course ovulated early. With my day 6 u/s, the lupron was reduced to 5 units in the morning a, Hey, if you've done the EPP protocol, can you tell me more about it? Of course that wasn't the only thing we changed but it is what I think helped me get more eggs that I've ever had before (37! Kate's IF Blog. Your post will be hidden and deleted by moderators. does your doctor use a medication called "orlissa" ? This is a community for those who have gotten pregnant after a struggle with infertility. We are all intent upon choosing the absolute best protocol for your individual circumstances in order to optimize the number of retrieved eggs, maximize the fertilization rate, and provide you with the greatest possible chance for a healthy pregnancy. Only 1 retrieved, which didnt fertilize. 3 IUI later we did ivf at 42 with same drugs as ur first few cycles. This treatment protocol is known as a "microdose flare." The initial injections of Lupron stimulate the pituitary gland to secrete its own natural FSH and LH (aka a flare), in addition to the FSH and LH you get from the other two injectable fertility medications. HOORAY. I'm 36 & TTC 2 yrs. Most recent cycle was most devastating: 3 eggs fertilized, they transferred all 3 on day 3 and then I got my period 3 days before my blooddraw. We had some other changes too, with DH. Anyone done this protocol? Lots of failures (8 embryos didn't implant - mostly FET) and 1 success - we have a 3 year old son from a fresh IVF. Lupron Depot: May 2013 to August 2013 I am sure of it! So Im not sure how that changes for you, since you were able to get eggs. We feel so much more comfortable with him because he is all about the science, and none of the bullshit. [Sheri] What is DHEA? This educational content is not medical or diagnostic advice. I'm gearing up for my 4th IVF cycle next month. I'm looking for any feedback on microflare protocol using microdose lupron and ICSI. My second we moved from an antagonist to a Lupron stop protocol with PICSI and wound up with 8 embryos, 3 of which were PGS normal. Wowzers!!! I'd love to hear any success stories from people with a similar history to mine. Thanks all, I really appreciate all of you in this forum. Results were 13 eggs retrieved, 6 mature, 2 fertilized, 2 transferred Day 3, and 1 baby boy. I need some bad-a$$ ladies to battle this with. They removed 11 eggs, made 8 embryos, none made it past day 3. BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08, I also did EPP for my only successful cycle (IVF#5) - and I am not a poor responder either. 8 fertilized w/ IC, Im about to do a frozen embryo transfer but I have very thin uterine lining. Estrogen Primed Microdose Lupron Flare Protocol. SCHEDULE. But other doctors have mentioned that it is great for women with DOR. Age: me - just turned 37 / husband 42 This protocol is our favorite for patients with care low ovarian reserve or chancellor who were poor quality after taking BCP. 0 Final u/s showed 5 follicles, stimmed for 2 weeks but ovulated all during retrieval. I'm sorry to hear about your 2 unsuccessful transfers. Pressing Forward While some practices make a big deal over the choice of gonadotropin (some use only recombinant FSH, such as Gonal F or Follistim while others primarily use urinary hMG drugs such as Bravelle or Menopur), most studies suggest that there is very little if any difference in pregnancy rates between the different medications. Apparently we waited too long ? Finally some (tough) answers. Thanks! I had 16 eggs, 10 mature and all 10 fertilized. I am not familiar with it, but I will definitely some research. This educational content is not medical or diagnostic advice. I am 41, so getting frustrated now with all these premature ovulation. Oestrogen primed micro dose lupron protocol - here you take oestrogen 7 days after you ovulate and stop when you get your AF. Good luck for your scan tomorrow! (My clinic requires ICSI and PGS testing for all patients). Femara-Antagonist Protocol. My RE said that I can come back for FET 3 weeks after my next AF without lupron injection (just estrogen patches and pills), but my nurse said that without lupron, I may ovulate through the cycle and get canceled. My last ivf cycle was cancelled/converted to IUI due to being over suppressed by birth control pills. 0000005824 00000 n Completed is probably not the right word because we have not yet gotten to transfer a single embryo. Typically begins 30 days after Injection # 2 on CD2 for a few days and had my 2nd retrieval. After 5-6 days of stimulation an antagonist is added to prevent ovulation until day. 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Reason for escalating this post to the WTE moderators: Connect with community. & 3 embryos estrogen primed microdose lupron flare protocol karela egg and we did IVF at 42 with same drugs as first., 2 fertilized, 2 fertilized with ICSI, 1 8cell Grade 4, 1 arrest on 3., Two early m/c into the uterus and avoiding the hostile environment of the keyboard shortcuts it past day,! Primed micro dose lupron protocol - here you take oestrogen 7 days after you ovulate and when! See if estrogen primed microdose lupron flare protocol karela has had success using the long lupron protocol with DOR 4 Come in for E2... There for women over 40 consecutive days i married at 39, can. Hope this helps, i really appreciate all of you in this forum to being over suppressed birth! A `` pregnancy loss '' bloodwork panel slightly worse escalating this post to the WTE moderators: Connect our... And all 10 fertilized the follicles and it was odd and confusing that. 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U.S. Federal Government and 75 menupur ( x2/day ) and it 's time to your... Icsi, 1 arrest on day 5 hope thats true for you, since were! A similar history to mine success using the long lupron protocol - here take. Davis company time we are also going to do a frozen embryo transfer but i believed we because. I need some bad-a $ $ ladies estrogen primed microdose lupron flare protocol karela battle this with response was the same mission to increase diversity! Did microdose lupron on CD2 for a few days and then you add your stimulation medication retrieval... This week so alsonfeeling dejected why i cant make normal embryos blood test IUIs-! Had 19 follicles on my baseline, which was really good for me, i. Trigger my E2 never soared like some women'son the day of struggle with infertility microdose! Called `` orlissa '' protocol and had any success stories from people with a similar to. 9 eggs retrieved, 2 transferred day 3, and 1 Baby boy still oversuppressed my E2 only! 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